Almost famous: Human adenoviruses (and what they have taught us about cancer)

Almost famous: Human adenoviruses (and what they have taught us about cancer)

Blog Article

Papillomaviruses, polyomaviruses and adenoviruses are collectively categorized as the small DNA tumour viruses.Notably, human adenoviruses were the first human viruses demonstrated to be able to cause cancer, albeit in non-human animal models.Despite their long history, no human adenovirus is a known causative agent of 03.2150.400 human cancers, unlike a subset of their more famous cousins, including human papillomaviruses and human Merkel cell polyomavirus.Nevertheless, seminal research using human adenoviruses has been highly informative in understanding the basics of funky chunky chocolate pretzels cell cycle control, gene expression, apoptosis and cell differentiation.

This review highlights the contributions of human adenovirus research in advancing our knowledge of the molecular basis of cancer.